Preimplantation genetic tests

Preimplantation genetic screening (PGS) is a lab technique that allows us to identify embryos carrying chromosomal abnormalities, the goal being to transfer only healthy embryos, conceived in vitro, in the patient’s uterus.

The PGD may be offered:

  • To older patients
  • To couples with a history of recurrent implantation failures
  • To couples with a history of recurrent unexplained miscarriages
  • In cases of severe male infertility

At Fertilys, we perform a trophectoderm biopsy on the embryo for PGD. This allows us to retrieve a few cells at the blastocyst stage (5-day embryo) for analysis.

Cell samples are then sent to a specialized lab. The results on the chromosomal status of the blastocysts are available after a few days. At that point, it’s possible to choose a healthy embryo and transfer it to the patient’s uterus.

fertilys clinique fertilite services depistage diagnostique preimplantatoire dpi cellulles

Frequently asked questions

  • Does genetic testing (PGT) guarantee 100% that my baby will be in perfect health?

    No. Preimplantation genetic testing can reduce the risk of passing on certain genetic or chromosomal abnormalities, but it cannot guarantee that a baby will be in perfect health. Like any medical test, PGT has its limitations and does not screen for all conditions that may arise during a child’s development.

  • Does embryo biopsy for genetic testing risk damaging or hindering its development?

    Embryo biopsy is a technique commonly used in the context of preimplantation genetic testing. When performed by experienced professionals, it carries a very low risk of affecting embryo development. While no procedure is entirely without risk, current techniques allow this procedure to be performed safely while preserving the best possible chances of embryo development.

  • Why is PGT particularly recommended after age 35 or 40, even if we have no known genetic condition?

    With age, the risk of eggs having chromosomal abnormalities increases, even in the absence of a family history or known genetic condition. This is why PGT may be offered after age 35 or 40 in certain situations. PGT helps identify embryos with certain chromosomal abnormalities, which can help guide the selection of the embryo to transfer and reduce the risk of miscarriage or implantation failure.

  • Does testing my embryos increase my chances of success from the first transfer?

    Preimplantation genetic testing can, in certain situations, increase the chances of success from the first transfer by allowing the selection of an embryo with a normal chromosome count. However, PGT does not improve embryo quality and does not guarantee a pregnancy. Its value depends on your age, medical history, and individual situation.

  • If I already have frozen embryos from a previous cycle, can I have them thawed for genetic testing today?

    Yes, in certain situations, it is possible to thaw previously frozen embryos in order to perform genetic testing, and then refreeze them before a transfer. However, this option is not appropriate in all cases. It depends in particular on the quality of the embryos, your medical situation, and your doctor’s assessment.

Find more questions in our FAQ